Site icd
- Name: icd
- Type: Gene
- Synonyms
b1136 MG1655 locus tag icdE - Mnemonic: isocitrate dehydrogenase
- Left End Point: 25.75
- Right End Point: 25.77
- Products:
isocitrate dehydrogenase, NADP+-specific - Direction: >
- Properties:
Property Comment e14 3' end derived from an e14 sequence - Priority: 1
- 3 Alleles of This Gene
icd-11 icd-3 icd-724(del)::kan - External Database Links:
Host Site Page Links NCBI/GenBank J02799 EcoGene.org EG10489 EcoliWiki icd - Comment:
- Selectable phenotype. Loss: low-level nalidixic acid resistance. In K-12, the 3' end has been replaced with a similar sequence from e14 and similar,presumed "old" 3' end is clockwise of pin and mcrA
- References:
- Helling, R.B., J. Kukora 1971. Nalidixic acid-resistant mutants of Escherichia coli deficient in isocitrate dehydrogenase. J.Bacteriol. 105:1224-1226
- Apostolakos, D., P.A. Menter, B.J. Rampsch, H.C. Reeves, E.A. Birge 1982. Genetic map position of the cistron coding for isocitrate dehydrogenase in Escherichia coli K-12. Curr.Microbiol. 7:45-47
- Hill, CW, JA Gray, H Brody 1989. Use of the isocitrate dehydrogenase structural gene for attachment of e14 in Escherichia coli K-12. J. Bacteriol. 171(7):4083-4.
- Herold, C., E.A. Birge 1990. Location of icdA and fadR on the physical map of Escherichia coli. J.Bacteriol. 172:6618
- Campbell, A., S.J. Schneider, B. Song 1992. Lambdoid phages as elements of bacterial genomes. Genetica 86:259-267
- Wang, FS, TS Whittam, RK Selander 1997. Evolutionary genetics of the isocitrate dehydrogenase gene (icd) in Escherichia coli and Salmonella enterica. J. Bacteriol. 179(21):6551-9.
- Prost, J.F., D. Negre, C. Oudot, K. Murakami, A. Ishihama, A.J. Cozzone, J.C. Cortay 1999. Cra-dependent transcriptional activation of the icd gene of Escherichia coli. J.Bacteriol. 181:893-898