Site ihfA
- Name: ihfA
- Type: Gene
- Synonyms
b1712 MG1655 locus tag hid himA - Mnemonic: Integration
- Left End Point: 38.66
- Right End Point: 38.66
- Products:
IHF integration host factor (IHF), alpha subunit - Direction: <
- Properties:
Property Comment transcription factor gene member of type 2 family, including HU, IHF, and subtilis phage SPO1's TF1 - Priority: 1
- 2 Alleles of This Gene
ihfA11::Tn10 ihfA786(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG10440 EcoliWiki ihfA - Comment:
- Selectable phenotype. Survival of infection with mutant phage LAM. Survival of induction of Mu cts prophage. Role in conjug.DNA transfer.Req.for glucose starv.survivalandinduct.of 14 prot.of stimulon
- References:
- Miller, H.I., D.I. Friedman 1977. Isolation of Escherichia coli mutants unable to support lambda integrative recombination, p. 349-356. In A.I. Bukhari, J.A. Shapiro, and S.L. Adhya (ed.), DNA insertion elements, plasmids and episomes. Cold Spr.Harb.Sy
- Miller, H.I., Y. Kikuchi, H.A. Nash, R. Weisberg, D.I. Friedman 1978. Site-specific recombination of bacteriophage lambda: the role of host gene products. Cold Spr.Harb.Symp.Quant.Biol. 43:1121-1126
- Miller, H.I., D.I. Friedman 1980. An E. coli gene product required for lambda site-specific recombination. Cell 20:711-719
- Miller, H.I., M. Kirk, H. Echols 1981. SOS induction and autoregulation of the himA gene for site-specific recombination in Escherichia coli. Proc.Natl.Acad.Sci.USA 78:6754-6758
- Miller, H.I., H.A. Nash 1981. Direct role of the himA gene product in phage lambda integration. Nature 290:523-526
- Comer, M.M. 1981. Gene organization around the phenylalanyl-transfer ribonucleic acid synthetase loci in Escherichia coli. J.Bacteriol. 146:269-274
- Mechulam, Y., G. Fayat, S. Blanquet 1985. Sequence of the E. coli pheST operon and identification of the himA gene. J.Bacteriol. 163:787-791
- Mechulam, Y., S. Blanquet, G. Fayat 1987. Dual level control of the Escherichia coli pheST-himA operon expression. tRNA$^{Phe}$-dependent attenuation and transcriptional operator-repressor control by himA and the SOS network. J.Mol.Biol. 197:453-470
- Biek, D.P., S.N. Cohen 1989. Involvement of integration host factor (IHF) in maintenance of plasmid pSC101 in Escherichia coli: mutations in the topA gene that allow pSC101 replication in the absence of IHF. J.Bacteriol. 171:2066-2074
- Biek, D.P., S.N. Cohen 1989. Involvement of integration host factor (IHF) in maintenance of plasmid pSC101 in Escherichia coli: characterization of pSC101 mutants that replicate in the absence of IHF. J.Bacteriol. 171:2056-2065
- Mendelson, I., M.M. Gottesman, A.B. Oppenheim 1991. HU and integration host factor function as auxiliary proteins in cleavage of phage lambda cohesive ends by terminase. J.Bacteriol. 173:1670-1676
- Lee, E.C., L.M. Hales, R.I. Gumport, J.F. Gardner 1992. The isolation and characterization of mutants of the integration host factor (IHF) of Escherichia coli with altered, expanded DNA-binding specificities. EMBO J. 11:305-313
- Charlier, D., M. Roovers, D. Gigot, N. Huysveld, A. Pierard, N. Glansdorff 1993. Integration host factor (IHF) modulates the expression of the pyrimidine-specific promoter of the carAB operons of Escherichia coli K12 and Salmonella typhimurium LT2. Mol
- Nystrom, T. 1995. Glucose starvation stimulon of Escherichia coli: role of integration host factor in starvation survival and growth phase-dependent protein synthesis. J.Bacteriol. 177:5707-5710
- Engelhorn, M., F. Boccard, C. Murtin, P. Prentki, J. Geiselmann 1995. In vivo interaction of the Escherichia coli integration host factor with its specific binding sites [corrected and republished with original paging, article originally printed in Nuc
- Goosen, N., P. van de Putte 1995. The regulation of transcription initiation by integration host factor. Mol.Microbiol. 16:1-7
- Weisberg, R., M. Freundlich, D.I. Friedman, J.F. Gardner, N. Goosen, H.A. Nash, A.B. Oppenheim, J. Rouviere-Yaniv 1996. Nomenclature of the genes encoding IHF. Mol.Microbiol. 19:642
- Hales, L.M., R.I. Gumport, J.F. Gardner 1996. Examining the contribution of a dA+dT element to the conformation of Escherichia coli integration host factor-DNA complexes. Nucleic Acids Res. 24:1780-1786
- Sukharev, S.I., P. Blount, B. Martinac, C. Kung 1997. Mechanosensitive channels of Escherichia coli: the MscL gene, protein, and activities. Annu Rev Physiol 59:633-657
- Polaczek, P., K. Kwan, J.L. Campbell 1998. Unwinding of the Escherichia coli origin of replication (oriC) can occur in the absence of initiation proteins but is stabilized by DnaA and histone-like proteins IHF or HU. Plasmid 39:77-83
- Dworkin, J., A.J. Ninfa, P. Model 1998. A protein-induced DNA bend increases the specificity of a prokaryotic enhancer-binding protein. Genes Dev. 12:894-900
- Grimwade, J.E., V.T. Ryan, A.C. Leonard 2000. IHF redistributes bound initiator protein, DnaA, on supercoiled oriC of Escherichia coli. Mol.Microbiol. 35:835-844