Site yidC
- Name: yidC
- Type: Gene
- Synonyms
b3705 MG1655 locus tag - Mnemonic: Temporary systematic nomenclature
- Left End Point: 83.69
- Right End Point: 83.73
- Direction: >
- Priority: 0
- External Database Links:
Host Site Page Links EcoGene.org EG11197 EcoliWiki yidC - Comment:
- membrane protein involved in insertion and assembly of membrane proteins. required for insertion of F1F0 ATP synthase subunit c
- References:
- Scotti, P.A., M.L. Urbanus, J. Brunner, J.W. de Gier, G. von Heijne, C. van der Does, A.J. Driessen, B. Oudega, J. Luirink 2000. YidC, the Escherichia coli homologue of mitochondrial Oxa1p, is a component of the Sec translocase. EMBO J. 19:542-549
- Luirink, J., T. Samuelsson, J.W. de Gier 2001. YidC/Oxa1p/Alb3: evolutionarily conserved mediators of membrane protein assembly. FEBS Lett. 501:1-5
- Koch, H.G., M. Moser, K.L. Schimz, M. Muller 2002. The integration of YidC into the cytoplasmic membrane of Escherichia coli requires the signal recognition particle, SecA and SecYEG. J.Biol.Chem. 277:5715-5718
- Urbanus, M.L., L. Froderberg, D. Drew, P. Bjork, J.W. de Gier, J. Brunner, B. Oudega, J. Luirink 2002. Targeting, insertion, and localization of Escherichia coli YidC. J.Biol.Chem. 277:12718-12723
- van der Laan, M., P. Bechtluft, S. Kol, N. Nouwen, A.J. Driessen 2004. F1F0 ATP synthase subunit c is a substrate of the novel YidC pathway for membrane protein biogenesis. J Cell Biol 165:213-222
- Xie, K., D. Kiefer, G. Nagler, R.E. Dalbey, A. Kuhn 2006. Different regions of the nonconserved large periplasmic domain of Escherichia coli YidC are involved in the SecF interaction and membrane insertase activity. Biochemistry 45:13401-13408
- Celebi, N., L. Yi, S.J. Facey, A. Kuhn, R.E. Dalbey 2006. Membrane biogenesis of subunit II of cytochrome bo oxidase: contrasting requirements for insertion of N-terminal and C-terminal domains. J.Mol.Biol. 357:1428-1436