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Site deoA
- Name: deoA
- Type: Gene
- Synonyms
b4382 MG1655 locus tag tpp-75 - Mnemonic: Deoxyribose
- Left End Point: 99.50
- Right End Point: 99.52
- Products:
thymidine phosphorylase - Direction: >
- Priority: 1
- 6 Alleles of This Gene
deoA0 deoA21 deoA22 deoA75 deoA778(del)::kan deoA91 - External Database Links:
Host Site Page Links EcoGene.org EG10219 EcoliWiki deoA - Comment:
- Selectable Phenotype. Loss, in upp-: deoxyadenosine + fluoraouracil resistance. In deoC-: thymidine resistance.
- References:
- Ahmad, S.I., R.H. Pritchard 1969. A map of four genes specifying enzymes involved in catabolism of nucleosides and deoxynucleosides in Escherichia coli. Mol.Gen.Genet. 104:351-359
- Valentin-Hansen, P., K. Hammer-Jespersen, R.S. Buxton 1979. Evidence for the existence of three promoters for the deo operon of Escherichia coli K12 in vitro. J.Mol.Biol. 133:1-17
- Valentin-Hansen, P., H. Aiba, D. Schumperli 1982. The structure of tandem regulatory regions in the deo operon of Escherichia coli K12. EMBO J. 1:317-322
- Fischer, M., S.A. Short 1982. The cloning of the Escherichia coli K-12 deoxyribonucleoside operon. Gene 17:291-298
- Valentin-Hansen, P., K. Hammer, E.L. Larsen, I. Svendsen 1984. The internal regulated promoter of the deo operon of Escherichia coli K-12. Nucleic Acids Res. 12:5211-5224
- Valentin-Hansen, P., K. Hammer-Jespersen, F. Boetius, I. Svendsen 1984. Structure and function of the intercistronic regulatory deoC-deoA element of Escherichia coli K-12. EMBO J. 3:179-183
- Sukhodolets, V.V., D.E. Dukhii 1996. [Unequal crossing over in Escherichia coli: genetic and physical mapping of duplications isolated in conjugational matings]. Genetika 32:42-52
- Esteban-Gamboa, A., J. Balzarini, R. Esnouf, E. De Clercq, M.J. Camarasa, M.J. Perez-Perez 2000. Design, synthesis, and enzymatic evaluation of multisubstrate analogue inhibitors of Escherichia coli thymidine phosphorylase. J Med Chem 43:971-983