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Site dadA
- Name: dadA
- Type: Gene
- Synonyms
b1189 MG1655 locus tag dadR - Mnemonic: D-amino acid dehydrogenase
- Left End Point: 26.66
- Right End Point: 26.69
- Products:
D-amino acid dehydrogenase subunit - Direction: <
- Priority: 1
- 4 Alleles of This Gene
dadA1(op) dadA237 dadA247(del) dadA778(del)::kan - External Database Links:
Host Site Page Links EcoGene.org EG11407 EcoliWiki dadA - Comment:
- Selectable Pheno. Deleted with fadR. Loss: B-chloro-D-alanine resistance. Constitutive in trp- or other amino acid auxotroph: use of D-tryptophan or other D-amino acid.
- References:
- Kuhn, J., R.L. Somerville 1971. Mutant strains of Escherichia coli K12 that can use D-amino acids. Proc.Natl.Acad.Sci.USA 68:2484-2487
- Wild, J.R., T. Klopotowski 1981. D-amino acid dehydrogenase of Escherichia coli K12: positive selection of mutants defective in enzyme activity and localization of the structural gene. Mol.Gen.Genet. 181:373-378
- Wild, J.R., B. Obrepalska 1982. Regulation of expression of the dadA gene encoding D-amino acid dehydrogenase in Escherichia coli: analysis of dadA-lac fusions and direction of dadA transcription. Mol.Gen.Genet. 186:405-410
- Wild, J.R., J. Henning, M. Lobockz, W. Walczak, T. Klopotowski 1985. Identification of the dadX gene coding for the predominant isozyme of alanine racemase in Escherichia coli K12. Mol.Gen.Genet. 198:315-322
- Wild, J.R., B. Zakrzewska, W. Walczak, T. Klopotowski 1987. Two distinct types of mutations conferring to Escherichia coli K12 capability of D-tryptophan utilization. Acta Microbiol.Pol. 36:17-28
- Lobocka, M., J. Hennig, J.R. Wild, T. Klopotowski 1994. Organization and expression of the Escherichia coli K-12 dad operon encoding the smaller subunit of D-amino acid dehydrogenase and the catabolic alanine racemase. J.Bacteriol. 176:1500-1510
- Mathew, E., J. Zhi, M. Freundlich 1996. Lrp is a direct repressor of the dad operon in Escherichia coli. J.Bacteriol. 178:7234-7240