Site tolC
- Name: tolC
- Type: Gene
- Synonyms
b3035 MG1655 locus tag colE1-i mtcB refI weeA - Mnemonic: Tolerance
- Left End Point: 68.46
- Right End Point: 68.50
- Products:
porin - Direction: >
- Priority: 1
- 6 Alleles of This Gene
tolC210::Tn10 tolC3 tolC5(del) tolC6::mini-Tn10 tolC732(del)::kan tolC832(del)::FRT - External Database Links:
Host Site Page Links NCBI/GenBank X54049 EcoGene.org EG11009 EcoliWiki tolC - Comment:
- Selectable phenotype. Bacteriocin tolerant. an outer membrane protein. (may form transporter or pore when complexed with HlyB and HlyC in inner membrane:Lory,JBac174:3423,1992)
- References:
- Foulds, J., E.L. Barrett 1973. Characterization of Escherichia coli mutants tolerant to bacteriocin JF246; two new classes of tolerant mutants. J.Bacteriol. 116:885-892
- Cardelli, J., J. Konisky 1974. Isolation and characterization of an Escherichia coli mutant tolerant to colicins Ia and Ib. J.Bacteriol. 119:379-385
- Davies, J.K., P.R. Reeves 1975. Genetics of resistance to colicins in Escherichia coli K-12: cross-resistance among colicins of group A. J.Bacteriol. 123:102-117
- Braun, V., J. Frenz, K. Hantke, H. Schaller 1980. Penetration of colicin M into cells of Escherichia coli. J.Bacteriol. 142:162-168
- Morona, R., P.R. Reeves 1981. Molecular cloning of the tolC locus of Escherichia coli K-12 with the use of transposon Tn10. Mol.Gen.Genet. 184:430-433
- Morona, R., P.R. Reeves 1982. The tolC locus of Escherichia coli affects the expression of three major outer membrane proteins. J.Bacteriol. 150:1016-1023
- Otsuji, N., T. Soejima, S. Maki, H. Shinagawa 1982. Cloning of colicin E1 tolerant tolC (mtcB) gene of Escherichia coli K12 and identification of its gene product. Mol.Gen.Genet. 187:30-36
- Hackett, J., R. Misra, P.R. Reeves 1983. The TolC protein of Escherichia coli K12 is synthesized in a precursor form. FEBS Lett. 156:307-310
- Hackett, J., P.R. Reeves 1983. Primary structure of the tolC gene that codes for an outer membrane protein of Escherichia coli K12. Nucleic Acids Res. 11:6487-6495
- de la Campa, A.G., M. Aldea, C. Hernandez-Chico, A. Tormo, M. Vicente 1988. Segregation of elongation potential in Escherichia coli mediated by the wee genetic system. Curr.Microbiol. 17:315-319
- Hiraga, S., H. Niki, T. Ogura, C. Ichinose, H. Mori, B. Ezaki, A. Jaffe 1989. Chromosome partitioning in Escherichia coli: novel mutants producing anucleate cells. J.Bacteriol. 171:1496-1505
- Niki, H., R. Imamura, T. Ogura, S. Hiraga 1990. Nucleotide sequence of the tolC gene of Escherichia coli. Nucleic Acids Res. 18:5547
- Wandersman, C., P. Delepelaire 1990. TolC, an Escherichia coli outer membrane protein required for hemolysin secretion. Proc.Natl.Acad.Sci.USA 87:4776-4780
- Yang, T.P., R.E. Depew 1992. Nucleotide sequence of a region duplicated in Escherichia coli toc mutants. Biochim.Biophys.Acta 1130:227-228
- Yang, T.P., R.E. Depew 1992. Physical map of the tolC-htrP region of the Escherichia coli chromosome. J.Bacteriol. 174:1700-1701
- Fralick, J.A. 1996. Evidence that TolC is required for functioning of the Mar/AcrAB efflux pump of Escherichia coli. J.Bacteriol. 178:5803-5805
- Barak, R., W.N. Abouhamad, M. Eisenbach 1998. Both acetate kinase and acetyl coenzyme A synthetase are involved in acetate-stimulated change in the direction of flagellar rotation in Escherichia coli. J.Bacteriol. 180:985-988