Site phoB
- Name: phoB
- Type: Gene
- Synonyms
b0399 MG1655 locus tag phoRc phoT - Mnemonic: Phosphate
- Left End Point: 8.98
- Right End Point: 8.99
- Products:
pho regulon positive response regulator - Direction: >
- Properties:
Property Comment regulatory gene NULL - Priority: 1
- 7 Alleles of This Gene
phoB52 phoB54 phoB55 phoB60 phoB62 phoB63 phoB763(del)::kan - External Database Links:
Host Site Page Links NCBI/GenBank X04026 EcoGene.org EG10728 EcoliWiki phoB - Comment:
- Selectable phenotype. Indicator plate. Loss: phage TC45 resistance. Activator protein for genes in phosphate regulon that carry the Pho box binding site. PhoB activated upon P'ylation by PhoR
- References:
- Wanner, B.L., P. Latterell 1980. Mutants affected in alkaline phosphatase expression: evidence for multiple positive regulators of the phosphate regulon in Escherichia coli. Genetics 96:353-366
- Wanner, B.L., S. Wieder, R. McSharry 1981. Use of bacteriophage transposon Mu d1 to determine the orientation for three proC-linked phosphate-starvation-inducible (psi) genes in Escherichia coli K-12. J.Bacteriol. 146:93-101
- Tommassen, J., B. Lugtenberg 1981. Localization of phoE, the structural gene for outer membrane protein e in Escherichia coli K-12. J.Bacteriol. 147:118-123
- Tommassen, J., P. deGeus, B. Lugtenberg, J. Hackett, P.R. Reeves 1982. Regulation of the pho regulon of Escherichia coli K-12. Cloning of the regulator genes phoB and phoR and identification of their gene products. J.Mol.Biol. 157:265-274
- Boidol, W., M. Simonis, M. Topert, G. Siewert 1982. Recombinant plasmids with genes for the biosynthesis of alkaline phosphatase of Escherichia coli. Mol.Gen.Genet. 185:510-512
- Makino, K., H. Shinagawa, A. Nakata 1982. Cloning and characterization of the alkaline phosphatase positive regulator gene (phoB) of Escherichia coli. Mol.Gen.Genet. 187:181-186
- Hadley, R.G., M. Hu, M. Timmons, K. Yun, R. Deonier 1983. A partial restriction map of the proA-purE region of the E. coli K-12 chromosome. Gene 22:281-287
- Shinagawa, H., K. Makino, A. Nakata 1983. Regulation of the pho regulon in Escherichia coli K-12. Genetic and physiological regulation of the positive regulatory gene phoB. J.Mol.Biol. 168:477-488
- Makino, K., H. Shinagawa, A. Nakata 1985. Regulation of the phosphate regulon of Escherichia coli K-12: regulation and role of the regulatory gene phoR. J.Mol.Biol. 184:231-240
- Makino, K., H. Shinagawa, M. Amemura, A. Nakata 1986. Nucleotide sequence of the phoB gene, the positive regulatory gene for the phosphate regulon of Escherichia coli K-12. J.Mol.Biol. 190:37-44
- Wanner, B.L., B.-D. Chang 1987. The phoBR operon in Escherichia coli K-12. J.Bacteriol. 169:5569-5574
- Jakubcionyte, E., D. Apirion, S. Normark 1993. Expression of the asr gene encoding acid shock RNA is controlled by the phoBR operon. GenBank submission L
- Wanner, B.L. 1993. Gene regulation by phosphate in enteric bacteria. J.Cell.Biochem. 51:47-54
- Kim, S.K., K. Makino, M. Amemura, A. Nakata, H. Shinagawa 1995. Mutational analysis of the role of the first helix of region 4.2 of the sigma 70 subunit of Escherichia coli RNA polymerase in transcriptional activation by activator protein PhoB. Mol.Gen
- Suziedeliene, E., K. Suziedelis, V. Garbenciute, S. Normark 1999. The acid-inducible asr gene in Escherichia coli: transcriptional control by the phoBR operon. J.Bacteriol. 181:2084-2093