Mutation polA480(ts,EX)
- Name: polA480(ts,EX)
- Type: Unknown
- Mutation of Gene: polA
- Approx. Map Location: 87.18
- Synonyms
Designation Where Used polAex1 - Properties
Property Symbol exonuclease activity mutation EX Temperature Sensitive ts - Comments
- lowered levels of polymerase, thermolabile in vitro; low levels Exo. see Grindley and Kelley, MGG 143:311.
- References
- Uyemura, D, DC Eichler, IR Lehman 1976. Biochemical characterization of mutant forms of DNA polymerase I from Escherichia coli. II. The polAex1 mutation. J. Biol. Chem. 251(13):4085-9.
- Grindley, ND, WS Kelley 1976. Effects of different alleles of the E. coli K12 pol A gene on the replication of non-transferring plasmids. Mol. Gen. Genet. 143(3):311-8.
- 1 Strains Carrying This Mutation
Name Mutations Genotype RS5064 4 F-, λ-, trpA33, IN(rrnD-rrnE)1, polA480(ts,EX)