Site proB
- Name: proB
- Type: Gene
- Synonyms
b0242 MG1655 locus tag pro2 - Mnemonic: Proline
- Left End Point: 5.60
- Right End Point: 5.62
- Products:
gamma-glutamyl kinase - Direction: >
- Properties:
Property Comment auxotrophy-amino acid NULL - Priority: 0
- 4 Alleles of This Gene
proB22 proB28 proB760(del)::kan proB91 - External Database Links:
Host Site Page Links NCBI/GenBank X00786 EcoGene.org EG10768 EcoliWiki proB - Comment:
- Selectable phenotype. Loss: 4-nitropyridine N-oxide resistance; deleted with lpcA; deleted with gpt. FBI-: dehydroproline, azetidine carboxylate resistance.
- References:
- Hirota, S., M. Inuzuka, M. Tomoeda 1966. Elective selection of proline-requiring mutants. J.Bacteriol. 91:2392
- Berg, C.M., J.J. Rossi 1974. Proline excretion and indirect suppression in Escherichia coli and Salmonella typhimurium. J.Bacteriol. 118:928-939
- VanAlphen, W., B. Lugtenberg, W. Berendsen 1976. Heptose-deficient mutants of Escherichia coli K12 deficient in up to three major outer membrane proteins. Mol.Gen.Genet. 147:263-269
- Fayerman, J.T., M.C. Vann, L.S. Williams, H.E. Umbarger 1979. ilvU, a locus in Escherichia coli affecting the derepression of isoleucyl-tRNA synthetase in the RPC-5 chromatographic profiles of tRNA^Ile and tRNA^Val. J.Biol.Chem. 254:9429-9440
- Hayzer, D.J., T. Leisinger 1980. The gene-enzyme relationships of proline biosynthesis in Escherichia coli. J.Gen.Microbiol. 118:287-293
- Csonka, L.N. 1981. Proline over-production results in enhanced osmotolerance in Salmonella typhimurium. Mol.Gen.Genet. 182:82-86
- Hadley, R.G., M. Hu, M. Timmons, K. Yun, R. Deonier 1983. A partial restriction map of the proA-purE region of the E. coli K-12 chromosome. Gene 22:281-287
- Mahan, M.J., L.N. Csonka 1983. Genetic analysis of the proBA genes of Salmonella typhimurium: physical and genetic analysis of the cloned proB+A+ genes of Escherichia coli and of a mutant allele that confers proline overproduction and enhanced osmotol
- Hayzer, D.J. 1983. Sub-cloning of the wild-type proAB region of the Escherichia coli genome. J.Gen.Microbiol. 129:3215-3225
- Rancourt, D.E., J.T. Stephenson, G.A. Vickell, J.M. Wood 1984. Proline excretion by Escherichia coli K12. Biotechnol.Bioeng. 26:74-80
- Deutch, A.H., K.E. Rushlow, C.J. Smith 1984. Analysis of the Escherichia coli proBA locus by DNA and protein sequencing. Nucleic Acids Res. 12:6337-6355
- Nersisyan, A.A., Y.A. Fedorova, E.M. Khurges 1986. Cloning of Escherichia coli genes for proline biosynthesis. Soviet Genet. 22:1493-1500