Site trpE
- Name: trpE
- Type: Gene
- Synonyms
anth b1264 MG1655 locus tag tryD tryp-4 - Mnemonic: tryptophan
- Left End Point: 28.44
- Right End Point: 28.47
- Products:
anthranilate synthase component I - Direction: <
- Properties:
Property Comment auxotrophy-amino acid - Priority: 1
- 13 Alleles of This Gene
trpE10220 trpE3(Oc) trpE38 trpE61 trpE63(del) trpE65(Oc) trpE68 trpE719(fbR) trpE772(del)::kan trpE81 trpE9829(Am) trpE9851(Oc) trpE9997 - External Database Links:
Host Site Page Links EcoGene.org EG11028 EcoliWiki trpE - Comment:
- Select. pheno. Operon: deleted withtonB; del. with opp. Const.: 5-methyltrptophan, 6-fluorotryptophan^R.FBI-: 3-methyl^R.;5-meth.^R. nuc.homol.40%,45% with pabB and entC, other chor.-bind.enz.
- References:
- Moyed, H.S. 1960. False feedback inhibition: inhibition of tryptophan biosynthesis by 5-methyltryptophan. J.Biol.Chem. 235:1098-1102
- Hiraga, S. 1969. Operator mutants of the tryptophan operon in Escherichia coli. J.Mol.Biol. 39:159-179
- Gottesman, S., J.R. Beckwith 1969. Directed transposition of the arabinose operon: a technique for the isolation of special transducing bacteriophages for any Escherichia coli gene. J.Mol.Biol. 44:117-127
- Held, W.A., O.H. Smith 1970. Mechanism of 3-methyl-anthranilic acid derepression of the tryptophan operon in Escherichia coli. J.Bacteriol. 101:209-217
- Mattern, I.E., J. Pittard 1971. Regulation of tyrosine biosynthesis in Escherichia coli K-12: isolation and characterization of operator mutants. J.Bacteriol. 107:8-15
- Oxender, D.L., G. Zurawski, C. Yanofsky 1979. Attenuation in the Escherichia coli tryptophan operon: role of RNA secondary structure involving the tryptophan codon region. Proc.Natl.Acad.Sci.USA 76:5524-5528
- Enger-Valk, B., H. Heyneker, R.A. Oosterbaan, P.H. Pouwels 1980. Construction of new cloning vehicles with genes of the tryptophan operon of Escherichia coli as genetic markers. Gene 9:69-85
- Nichols, B., G.F. Miozzari, M. van Cleemput, G. Bennett, C. Yanofsky 1980. Nucleotide sequences of the trpG regions of Escherichia coli, Shigella dysenteriae, Salmonella typhimurium and Serratia marcescens. J.Mol.Biol. 142:503-517
- Nichols, B., M. van Cleemput, C. Yanofsky 1981. Nucleotide sequence of Escherichia coli trpE. Anthranilate synthetase component I contains no tryptophan residues. J.Mol.Biol. 146:45-54
- Yanofsky, C., T. Platt, I.P. Crawford, B. Nichols, G.E. Christie, H. Horowitz, M. VanCleemput, A.M. Wu 1981. The complete nucleotide sequence of the tryptophan operon of E. coli. Nucleic Acids Res. 9:6647-6668
- Pogliano, J.A., J.R. Beckwith 1994. SecD and SecF facilitate protein export in Escherichia coli. EMBO J. 13:554-561